by Dr. Leon Katz / June 16 2024

You may have noticed or heard people talking about “Ozempic Face or Ozempic butt”. Let’s take a deep dive to understand what this means and what can be done about it.

As a medical professional, I'd like to address a topic that's been circulating on social media: the phenomena known as "Ozempic Face" or "Ozempic Butt." These terms refer to the skin laxity that can occur with rapid weight loss, often associated with GLP-1 receptor agonists like Ozempic, Wegovy, Zepbound, and Mounjaro.

Simple explanation

Think of your skin like a balloon. When you blow up a balloon, it stretches. If you let out some air, the balloon might look wrinkly. Your skin is kind of the same way.

The Science Behind Loose Skin

When significant weight loss occurs, whether through diet, medication, or surgery, both fat and muscle are reduced. Subcutaneous fat, which lies directly beneath the skin, plays a crucial role in maintaining skin firmness. As this fat layer diminishes, the skin may begin to sag (1).

Factors Influencing Skin Elasticity

Several factors affect how well your skin adapts to weight loss:

• Age

• Duration of obesity

• Initial degree of obesity

• Smoking history

Younger individuals generally have greater skin elasticity. Conversely, those who have been obese for extended periods or who smoke may experience more pronounced skin laxity.

Addressing Skin Laxity

While exercise can help in minor cases by building muscle to fill the space left by fat loss, it's not always sufficient for significant skin sagging. Here are some evidence-based approaches to manage skin laxity (2):

• Maintain proper hydration

• Consume a nutrient-rich diet, especially vitamins C, E and

zinc

• Cease smoking

• Engage in resistance training

• Consider non-invasive skin tightening procedures such as laser therapy, ultrasound, and radio-frequency treatments can help tighten skin (consult a dermatologist or plastic surgeon)

• In severe cases, surgical intervention may be necessary

A Positive Perspective

It's important to remember that some degree of skin laxity is a normal consequence of significant weight loss. Rather than viewing it negatively, consider it a sign of your successful journey towards improved health and longevity.

Always consult with your healthcare provider before making any significant changes to your health regimen. The information provided here is for educational purposes and does not constitute medical advice.