Oral GLP-1 Weight Loss Medications: A New Era in Weight Loss?
There's been a lot of buzz lately about new oral medications for weight loss that work similarly to popular injectables like Wegovy and Zepbound. But are they really as effective?
When you take medication by mouth, it must go through your stomach and liver before it reaches your brain and other key areas that control hunger. This process means some of the medicine is lost along the way, which is why injectables, like Wegovy, have been more effective until now.
Rybelsus, the oral form of Wegovy, works but at a much lower dose (14 mg). To achieve similar weight loss to Wegovy, higher doses are needed. A recent study showed that people taking 50 mg of oral semaglutide (Rybelsus) lost about 15% of their body weight over 68 weeks. This is close to the weight loss seen with injections. However, some patients did experience side effects like nausea, though these usually go away over time.
Novo Nordisk is also working on a new medication called Amycretin, combining two hormones. In early trials, people lost up to 13% of their body weight in just 12 weeks, which is promising.
While this is exciting, it's still too early to say oral medications will replace injections. More research is needed, but the future of weight loss treatment looks very promising!
For more information, please check out the full article at: https://www.linkedin.com/in/leon-katz-5484843b/
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